Bionemo FrameworkApplication · Nvidia

CVE-2026-24164

CRITICAL · 9.8 CVSS v3.1 Published 2026-03-31
Fix available
A fix is available. Upgrade to 2026-01-21 or later.
See remediation →
100/100
Remediation priority · Urgent
Remotely reachable No privileges Zero-click

Official description Straight from the sourceThe vendor's or NVD's own wording, published unedited. Authoritative, but often terse — it says what broke, rarely what to do.

NVD · unedited
NVIDIA BioNeMo contains a vulnerability where a user could cause a deserialization of untrusted data. A successful exploit of this vulnerability might lead to code execution, denial of service, information disclosure, and data tampering.

Technical summary Written by usOur analysis, written from the advisory, the CVSS vector and the affected-version data. It adds context the advisory leaves out, and never invents facts that are not in the source.

dbcve analysis · moderate confidence

NVIDIA BioNeMo contains an insecure deserialization vulnerability where the application deserializes data without proper validation. This allows attackers to potentially execute arbitrary code, cause denial of service, disclose information, or tamper with data by supplying maliciously crafted serialized objects.

MitigationValidate all deserialized data, implement allowlist-based deserialization, or migrate to safer data formats (JSON, XML without external entity processing). Apply vendor patches when available.

Verify against the referenced sources before acting — the references below are authoritative for this CVE, this summary is not.

Affected products & versions What the vendor confirmedThe version ranges the vendor confirmed as vulnerable. If your version sits inside a range here, treat yourself as exposed until you have upgraded.

NVD · CPE data
Bionemo FrameworkApplication
Affected:< 2026-01-21

CVSS breakdown How the score is builtThe industry scoring standard. It rates how the flaw is reached, what it takes to exploit, and what an attacker gains — the score is derived from those, not the other way round.

From the vector
Attack vector
Network
Complexity
Low
Privileges
None
User interaction
None
Scope
Unchanged
Confidentiality
High
Integrity
High
Availability
High

CVSS:3.1/AV:N/AC:L/PR:N/UI:N/S:U/C:H/I:H/A:H

Am I affected? How to checkSteps we derive from the advisory and the affected-version data, so you can decide whether this CVE reaches your setup. They are a guide, not a scan — your own configuration is the authority.

dbcve checks

Work through these to decide whether this CVE applies to you.

  1. Identify if BioNeMo Framework is installed
    Locate the BioNeMo installation directory or check for BioNeMo packages in your environment
    Affected if BioNeMo Framework is present on the system
  2. Determine the installed BioNeMo version
    Use the package manager, version command, or check release notes to identify the exact version number of the BioNeMo Framework
    Affected if The version is less than 2026-01-21 or the version cannot be determined but BioNeMo is present
  3. Identify deserialization endpoints
    Review API endpoints, service configurations, or data import features that accept serialized input (pickle, YAML, XML, or custom formats)
    Affected if The system exposes endpoints accepting serialized data from untrusted sources
  4. Inspect serialization configuration
    Check application configuration files and code for usage of unsafe deserialization methods without validation layers
    Affected if Unsafe deserialization is used without input validation or safe format restrictions

The environment is affected if BioNeMo Framework version is below 2026-01-21 AND the system processes untrusted serialized data through exposed endpoints or features.

Generated from the published advisory. Verify against your own configuration.

Check your environment

Paste your version and any relevant configuration and it will be compared against the affected criteria above. Do not include secrets or credentials.

AI-assisted, checked against the advisory. Informational, not a guarantee.

Remediation Closing itWhat it takes to close this. Where a vendor fix exists we point at it; where none exists we say so plainly, and can build one. Effort estimates are scoped from the advisory, not from your codebase.

dbcve · scoped
Upgrade available Upgrade to 2026-01-21 or later
Fixed in 2026-01-21
Interim mitigation

Validate all deserialized data, implement allowlist-based deserialization, or migrate to safer data formats (JSON, XML without external entity processing). Apply vendor patches when available.

Recommended fix High confidence

BioNeMo Framework version 2026-01-21 or later

  1. 1. Identify the current installed version of NVIDIA BioNeMo Framework by checking the package manifest or using the version command
  2. 2. Ensure all running instances of BioNeMo are stopped before updating
  3. 3. Upgrade to BioNeMo Framework version 2026-01-21 or later using the standard upgrade procedure (e.g., pip install --upgrade bionemo or the appropriate package manager for your deployment)
  4. 4. Verify the new version is correctly installed by checking the version number
  5. 5. Restart all BioNeMo services and confirm normal operation
  6. 6. Validate that the deserialization vulnerability is no longer present by reviewing release notes for the fixed version
Caveat Review NVIDIA's release notes for version 2026-01-21 for any potential compatibility changes or migration requirements

Generated from the published advisory — verify against the referenced sources before acting.

Fix this in Bionemo Framework Scoped from the published advisory
  • Consultation4.0 h
  • Implementation8.0 h
  • Testing6.0 h
  • Review / QA4.0 h
22.0 hours of engineering $3,860
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References Go to the primary sourcePrimary sources — vendor advisories, patches and trackers. Where our summary and a reference disagree, the reference wins.

Primary sources

Practitioner notes

Contributed

Peer-ranked notes from engineers who’ve handled CVE-2026-24164 in production — separate from our analysis above.

No notes yet

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What this is

A place for practitioners to share what actually worked: a mitigation you’ve tested, a configuration change, a version- or environment-specific caveat, or a link to a verified patch. The most useful notes rise to the top as peers upvote them, so the signal stays high.

What belongs here
  • Verified mitigations, workarounds, and config changes
  • Version or environment caveats, and links to real fixes
  • No weaponised exploit code, or anything meant to cause harm
  • No spam, self-promotion, credentials, or personal data